# Find some error while following the protein ligand simulation

**URL:** <https://gromacs.bioexcel.eu/t/find-some-error-while-following-the-protein-ligand-simulation/10888>\
**Category:** User discussions\
**Created:** [December 23, 2024, 9:09am UTC](https://gromacs.bioexcel.eu/t/find-some-error-while-following-the-protein-ligand-simulation/10888 "2024-12-23T09:09:19Z")\
**Posts on this page:** 4\
**Page:** 1

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**Author:** ![Deep](https://avatars.discourse-cdn.com/v4/letter/d/ce7236/32.png) [@Deep](https://gromacs.bioexcel.eu/u/Deep)\
**Post date:** [December 23, 2024, 9:09am UTC](https://gromacs.bioexcel.eu/t/find-some-error-while-following-the-protein-ligand-simulation/10888/1 "2024-12-23T09:09:19Z")

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python cgenff\_charmm2gmx.py JZ4 jz4\_fix.mol2 jz4.str charmm36-jul2022.ff  
python: can’t open file ‘/mnt/c/Users/DEEP/OneDrive/Documents/sim\_tuti/cgenff\_charmm2gmx.py’: [Errno 2] No such file or directory. Please suggest some solution to fix this.

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**Author:** ![obZehn](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/obzehn/32/2629_2.png) [@obZehn](https://gromacs.bioexcel.eu/u/obZehn)\
**Post date:** [December 23, 2024, 3:33pm UTC](https://gromacs.bioexcel.eu/t/find-some-error-while-following-the-protein-ligand-simulation/10888/2 "2024-12-23T15:33:02Z")

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This is not really GROMACS related but rather an error of python. As the error suggests, the script cannot be found in the directory where you are running the command. Are you in the right directory?

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**Author:** ![Deep](https://avatars.discourse-cdn.com/v4/letter/d/ce7236/32.png) [@Deep](https://gromacs.bioexcel.eu/u/Deep)\
**Post date:** [December 26, 2024, 4:41pm UTC](https://gromacs.bioexcel.eu/t/find-some-error-while-following-the-protein-ligand-simulation/10888/3 "2024-12-26T16:41:09Z")

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yes. I am in the right directory

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**Author:** ![obZehn](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/obzehn/32/2629_2.png) [@obZehn](https://gromacs.bioexcel.eu/u/obZehn)\
**Post date:** [December 30, 2024, 9:35am UTC](https://gromacs.bioexcel.eu/t/find-some-error-while-following-the-protein-ligand-simulation/10888/4 "2024-12-30T09:35:18Z")

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Can you post the content of the directory from where you are launching the command? Are you using the correct python version for the script you are using?