# ForceField for Intrisically disordered protein

**URL:** <https://gromacs.bioexcel.eu/t/forcefield-for-intrisically-disordered-protein/13470>\
**Category:** User discussions\
**Created:** [May 20, 2026, 2:28pm UTC](https://gromacs.bioexcel.eu/t/forcefield-for-intrisically-disordered-protein/13470 "2026-05-20T14:28:57Z")\
**Posts on this page:** 1\
**Showing post:** 8

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**Author:** ![Karis](https://avatars.discourse-cdn.com/v4/letter/k/ed8c4c/32.png) [@Karis](https://gromacs.bioexcel.eu/u/Karis)\
**Post date:** [May 21, 2026, 6:08pm UTC](https://gromacs.bioexcel.eu/t/forcefield-for-intrisically-disordered-protein/13470/8 "2026-05-21T18:08:22Z")

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See [Is it allowed to use Charmm36 ff on protein and GAFF on ligand? - #2 by MagnusL](https://gromacs.bioexcel.eu/t/is-it-allowed-to-use-charmm36-ff-on-protein-and-gaff-on-ligand/10428/2) . Typically for CHARMM you want to use CGENFF specifically. I recall charmmgui giving you a choice for which forcefields to use for the ligand but don’t remember which ones are available, but they likely set the correct one for you by default.

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