# How many repeats of normal MD correspond to an REMD?

**URL:** https://gromacs.bioexcel.eu/t/how-many-repeats-of-normal-md-correspond-to-an-remd/3312
**Category:** User discussions
**Created:** [December 15, 2021, 4:07pm UTC](https://gromacs.bioexcel.eu/t/how-many-repeats-of-normal-md-correspond-to-an-remd/3312 "2021-12-15T16:07:00Z")
**Posts on this page:** 1
**Page:** 1

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### Author: ![lanselibai](https://avatars.discourse-cdn.com/v4/letter/l/e9c0ed/32.png) [@lanselibai](https://gromacs.bioexcel.eu/u/lanselibai)
#### Post date: [December 15, 2021, 4:07pm UTC](https://gromacs.bioexcel.eu/t/how-many-repeats-of-normal-md-correspond-to-an-remd/3312/1 "2021-12-15T16:07:00Z")

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GROMACS version:2021  
GROMACS modification: No  
Here post your question

My understanding for the REMD is, it can be more sufficient to explore the possible conformation by exchanging with replica at higher temperatures.

Can I ask is that possible if I can tell how many repeats of normal MD correspond to one REMD? For example, if I provide the parameters for the REMD (e.g. replica, temperature, REMD duration, etc.), I can estimate it corresponds to the sampling size of e.g. 10 repeats of normal MD?