# Mdp parameters for non-bonded interaction using the AMBER force field

**URL:** <https://gromacs.bioexcel.eu/t/mdp-parameters-for-non-bonded-interaction-using-the-amber-force-field/6458>\
**Category:** User discussions\
**Tags:** forcefield, mdp-parameters, simulation-setup\
**Created:** [May 20, 2023, 3:40pm UTC](https://gromacs.bioexcel.eu/t/mdp-parameters-for-non-bonded-interaction-using-the-amber-force-field/6458 "2023-05-20T15:40:40Z")\
**Posts on this page:** 1\
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**Author:** ![dbischoff](https://avatars.discourse-cdn.com/v4/letter/d/b5ac83/32.png) [@dbischoff](https://gromacs.bioexcel.eu/u/dbischoff)\
**Post date:** [May 24, 2023, 7:08am UTC](https://gromacs.bioexcel.eu/t/mdp-parameters-for-non-bonded-interaction-using-the-amber-force-field/6458/2 "2023-05-24T07:08:10Z")

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Hey,

> [@Eduardneu](#):
>
> Doing some further research a came across [this website](https://computecanada.github.io/molmodsim-md-theory-lesson-novice/aio/index.html#how-to-choose-the-appropriate-cutoff-distance) that explained how to choose the appropriate cutoff distance. For the AMBER force field, it is 10 Å or 1 nm. The cutoff value depends on the cutoff which was used during the parametrization of the force field. As stated in the primary literature [ff99SB](https://onlinelibrary.wiley.com/doi/10.1002/prot.21123), [ff14SB](https://pubs.acs.org/doi/10.1021/acs.jctc.5b00255), [ff19SB](https://pubs.acs.org/doi/10.1021/acs.jctc.9b00591) and [lipids21](https://pubs.acs.org/doi/10.1021/acs.jctc.1c01217) were all parameterized using a cutoff value of 10 Å or 1 nm, respectively.

In case you are working with ff14SB, I think that one uses 8 Å cutoff for non-bonded interactions:  
“Nonbonded interactions were calculated directly up to 8 Å.” from the ff14SB publication.

Please correct me if I am missing something.

Regards  
Daniel

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