# NVIDIA ADA gpu (5070 ti and 5080) failed to be used during simulation in gromacs 2024.4

**URL:** <https://gromacs.bioexcel.eu/t/nvidia-ada-gpu-5070-ti-and-5080-failed-to-be-used-during-simulation-in-gromacs-2024-4/12837>\
**Category:** User discussions\
**Tags:** gpu, installation\
**Created:** [October 27, 2025, 10:29am UTC](https://gromacs.bioexcel.eu/t/nvidia-ada-gpu-5070-ti-and-5080-failed-to-be-used-during-simulation-in-gromacs-2024-4/12837 "2025-10-27T10:29:44Z")\
**Posts on this page:** 1\
**Showing post:** 2

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**Author:** ![obZehn](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/obzehn/32/2629_2.png) [@obZehn](https://gromacs.bioexcel.eu/u/obZehn)\
**Post date:** [October 27, 2025, 12:42pm UTC](https://gromacs.bioexcel.eu/t/nvidia-ada-gpu-5070-ti-and-5080-failed-to-be-used-during-simulation-in-gromacs-2024-4/12837/2 "2025-10-27T12:42:45Z")

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I think this is answered here.

> [@GROMACS 2023.4 on RTX5080](https://gromacs.bioexcel.eu/t/gromacs-2023-4-on-rtx5080/12755/2):
>
> Hi, Forward compatibility with new architectures has indeed been broken in GROMACS 2022-2024.6, see the [release note](https://manual.gromacs.org/current/release-notes/2024/2024.6.html#fix-cuda-ptx-generation-for-new-architectures). Using -DGMX\_CUDA\_TARGET\_SM=120 should help: you will compile the code specifically for your GPU. If that fails (there could be issues, haven’t tested), -DGMX\_CUDA\_TARGET\_COMPUTE=80 is a more gentle fix: it will compile the code for the old architecture but in a forward-compatible way (how it should have worked if not for that bug).

Try with GROMACS 2024.6 or one of the 2025.x versions!

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