# Parameter files **URL:** \ **Category:** User discussions\ **Tags:** mdp-parameters\ **Created:** [December 14, 2021, 6:05pm UTC](https://gromacs.bioexcel.eu/t/parameter-files/3305 "2021-12-14T18:05:45Z")\ **Posts on this page:** 3\ **Page:** 1
**Author:** ![Suraj](https://avatars.discourse-cdn.com/v4/letter/s/ecccb3/32.png) [@Suraj](https://gromacs.bioexcel.eu/u/Suraj)\ **Post date:** [December 14, 2021, 6:05pm UTC](https://gromacs.bioexcel.eu/t/parameter-files/3305/1 "2021-12-14T18:05:45Z")
GROMACS version:2020.1-Ubuntu-2020.1-1 GROMACS modification: No Question- Can we use default mdp parameter files present online for all proteins and protein-ligand complex? If no, how will set the parameters and its values? ---
**Author:** ![jalemkul](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/jalemkul/32/18_2.png) [@jalemkul](https://gromacs.bioexcel.eu/u/jalemkul)\ **Post date:** [December 15, 2021, 1:41pm UTC](https://gromacs.bioexcel.eu/t/parameter-files/3305/2 "2021-12-15T13:41:00Z")
No. Each force field has its own requirements for appropriate cutoffs, treatment of constraints, long-range corrections, etc. The defaults provide a plausible set of values that may be suitable but you should **not** assume these values are valid for any particular purpose. You need to understand the force field you’re using and assign the settings appropriately. ---
**Author:** ![Suraj](https://avatars.discourse-cdn.com/v4/letter/s/ecccb3/32.png) [@Suraj](https://gromacs.bioexcel.eu/u/Suraj)\ **Post date:** [December 15, 2021, 2:32pm UTC](https://gromacs.bioexcel.eu/t/parameter-files/3305/3 "2021-12-15T14:32:14Z")
Ok. I will do a research on selecting parameter values. Again thank you.