# Please guide me step by step on how to use plumed in gromacs and run multiple simulation

**URL:** <https://gromacs.bioexcel.eu/t/please-guide-me-step-by-step-on-how-to-use-plumed-in-gromacs-and-run-multiple-simulation/4541>\
**Category:** User discussions\
**Created:** [August 2, 2022, 10:40am UTC](https://gromacs.bioexcel.eu/t/please-guide-me-step-by-step-on-how-to-use-plumed-in-gromacs-and-run-multiple-simulation/4541 "2022-08-02T10:40:41Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Jeancolar11](https://avatars.discourse-cdn.com/v4/letter/j/278dde/32.png) [@Jeancolar11](https://gromacs.bioexcel.eu/u/Jeancolar11)\
**Post date:** [August 2, 2022, 10:40am UTC](https://gromacs.bioexcel.eu/t/please-guide-me-step-by-step-on-how-to-use-plumed-in-gromacs-and-run-multiple-simulation/4541/1 "2022-08-02T10:40:42Z")

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Please guide me step by step on how to use plumed in gromacs and run multiple simulation at once . I am a newbie and I cant understand anything that has been given in plumed tutorial .

So please anyone guide me in easy words step by step .  
My system is PROTEIN+RNA+COFACTOR complex  
GROMACS version:2022  
GROMACS modification: Yes/No  
Here post your question

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**Author:** ![hess](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/hess/32/416_2.png) [@hess](https://gromacs.bioexcel.eu/u/hess)\
**Post date:** [August 10, 2022, 12:59pm UTC](https://gromacs.bioexcel.eu/t/please-guide-me-step-by-step-on-how-to-use-plumed-in-gromacs-and-run-multiple-simulation/4541/2 "2022-08-10T12:59:55Z")

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This is a question for plumed, not for the GROMACS forum.