# Protein-DNA binding free energy Calculation tutorial

**URL:** <https://gromacs.bioexcel.eu/t/protein-dna-binding-free-energy-calculation-tutorial/2520>\
**Category:** User discussions\
**Tags:** analysis-tools\
**Created:** [July 16, 2021, 7:11am UTC](https://gromacs.bioexcel.eu/t/protein-dna-binding-free-energy-calculation-tutorial/2520 "2021-07-16T07:11:07Z")\
**Posts on this page:** 1\
**Page:** 1

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**Author:** ![jimzz](https://avatars.discourse-cdn.com/v4/letter/j/f0a364/32.png) [@jimzz](https://gromacs.bioexcel.eu/u/jimzz)\
**Post date:** [July 16, 2021, 7:11am UTC](https://gromacs.bioexcel.eu/t/protein-dna-binding-free-energy-calculation-tutorial/2520/1 "2021-07-16T07:11:07Z")

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GROMACS version:5.1.4  
GROMACS modification: No

Hi guys,

Is there any comphresive tutorial about calculating binding free energy for DNA-Protein System using gromacs or other tools?