# Protein placement in membrane

**URL:** <https://gromacs.bioexcel.eu/t/protein-placement-in-membrane/8344>\
**Category:** User discussions\
**Created:** [February 15, 2024, 3:17pm UTC](https://gromacs.bioexcel.eu/t/protein-placement-in-membrane/8344 "2024-02-15T15:17:18Z")\
**Posts on this page:** 3\
**Page:** 1

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**Author:** ![amiel](https://avatars.discourse-cdn.com/v4/letter/a/8baadc/32.png) [@amiel](https://gromacs.bioexcel.eu/u/amiel)\
**Post date:** [February 15, 2024, 3:17pm UTC](https://gromacs.bioexcel.eu/t/protein-placement-in-membrane/8344/1 "2024-02-15T15:17:18Z")

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GROMACS version:2022.5  
GROMACS modification: No  
Dear Gromacs users,

I am studying a protein in interaction with a receptor ing CG (Martini2). The receptor should be inserted in membrane through two alpha helices; is it possible to insert those two helices only in the membrane with insane or other techniques ?

When i add the membrane with insane the whole protein is inserted in the membrane.

Thank you for your help.  
Regards.

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**Author:** ![FarzaneJP](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/farzanejp/32/1211_2.png) [@FarzaneJP](https://gromacs.bioexcel.eu/u/FarzaneJP)\
**Post date:** [February 15, 2024, 3:54pm UTC](https://gromacs.bioexcel.eu/t/protein-placement-in-membrane/8344/2 "2024-02-15T15:54:40Z")

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For help with the initial setup, it’s best to ask your question in the MARTINI forum. You can also use CHARMM-GUI to easily put the protein’s CG model into the membrane.

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**Author:** ![amiel](https://avatars.discourse-cdn.com/v4/letter/a/8baadc/32.png) [@amiel](https://gromacs.bioexcel.eu/u/amiel)\
**Post date:** [February 15, 2024, 4:07pm UTC](https://gromacs.bioexcel.eu/t/protein-placement-in-membrane/8344/3 "2024-02-15T16:07:18Z")

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Thank you very much for your reply;