# Query regarding gmx error for sld.prm file while generating ions.tpr file

**URL:** https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698
**Category:** User discussions
**Created:** [August 24, 2020, 1:21pm UTC](https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698 "2020-08-24T13:21:19Z")
**Posts on this page:** 5
**Page:** 1

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### Author: ![deetijyothi1](https://avatars.discourse-cdn.com/v4/letter/d/3da27b/32.png) [@deetijyothi1](https://gromacs.bioexcel.eu/u/deetijyothi1)
#### Post date: [August 24, 2020, 1:21pm UTC](https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698/1 "2020-08-24T13:21:19Z")

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GROMACS version:2020.3  
GROMACS modification: Yes/No

when I am running the command:  
$ gmx\_mpi grompp -f ions.mdp -c solv.gro -p topol.top -o ions.tpr  
I am getting error like:  
ERROR 1 [file sld.prm, line 4]:  
Unknown bond\_atomtype CG2C1  
How to sort out this

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### Author: ![jalemkul](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/jalemkul/32/18_2.png) [@jalemkul](https://gromacs.bioexcel.eu/u/jalemkul)
#### Post date: [August 24, 2020, 5:43pm UTC](https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698/2 "2020-08-24T17:43:20Z")

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Where did this `.prm` file come from? Did you modify it in any way? CG2C1 is not a valid atom type in CGenFF.

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### Author: ![deetijyothi1](https://avatars.discourse-cdn.com/v4/letter/d/3da27b/32.png) [@deetijyothi1](https://gromacs.bioexcel.eu/u/deetijyothi1)
#### Post date: [August 25, 2020, 4:22am UTC](https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698/3 "2020-08-25T04:22:09Z")

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.prm file will generate when we run the command ‘python cgenff\_charmm2gmx.py JZ4 jz4\_fix.mol2 jz4.str charmm36-mar2019.ff’. Can anyone please suggest to me, do we need to add hydrogens for docking complex separated protein-ligand files before starting MDS? Thanks in advance.

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### Author: ![jalemkul](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/jalemkul/32/18_2.png) [@jalemkul](https://gromacs.bioexcel.eu/u/jalemkul)
#### Post date: [August 25, 2020, 3:01pm UTC](https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698/4 "2020-08-25T15:01:05Z")

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For CHARMM, which is an all-atom force field, yes.

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### Author: ![deetijyothi1](https://avatars.discourse-cdn.com/v4/letter/d/3da27b/32.png) [@deetijyothi1](https://gromacs.bioexcel.eu/u/deetijyothi1)
#### Post date: [September 9, 2020, 2:21pm UTC](https://gromacs.bioexcel.eu/t/query-regarding-gmx-error-for-sld-prm-file-while-generating-ions-tpr-file/698/5 "2020-09-09T14:21:30Z")

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Greetings!!!  
Yes. I used CHARMM36 all-atom force field (July 2017)
