# Simulation of condensate system with 100 chains of protein **URL:** \ **Category:** User discussions\ **Tags:** forcefield, mdrun, simulation-setup\ **Created:** [July 4, 2023, 5:22am UTC](https://gromacs.bioexcel.eu/t/simulation-of-condensate-system-with-100-chains-of-protein/6747 "2023-07-04T05:22:53Z")\ **Posts on this page:** 1\ **Page:** 1
**Author:** ![kesavanekambaram](https://avatars.discourse-cdn.com/v4/letter/k/67e7ee/32.png) [@kesavanekambaram](https://gromacs.bioexcel.eu/u/kesavanekambaram)\ **Post date:** [July 4, 2023, 5:22am UTC](https://gromacs.bioexcel.eu/t/simulation-of-condensate-system-with-100-chains-of-protein/6747/1 "2023-07-04T05:22:53Z")
GROMACS version:2022-beta1 GROMACS modification: No Hi All, I am trying to work on the condensate system where I have converted the C-alpha atoms of 100 proteins from the coarse-grained simulations into all atom model. Now I tried minimizing the system using the GROMACS with Amber-disp force field to study the intermolecular interactions between the protein chains. But, the system is not getting minimized. em.log ```auto Step Time 14 14.00000 Energy minimization has stopped because the force on at least one atom is not finite. This usually means atoms are overlapping. Modify the input coordinates to remove atom overlap or use soft-core potentials with the free energy code to avoid infinite forces. ``` The size of the system is 2029072 atoms Could anyone help me out in this regard? Thank you