# System is not equillibriating well

**URL:** <https://gromacs.bioexcel.eu/t/system-is-not-equillibriating-well/9308>\
**Category:** User discussions\
**Created:** [June 5, 2024, 9:36am UTC](https://gromacs.bioexcel.eu/t/system-is-not-equillibriating-well/9308 "2024-06-05T09:36:45Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Vignesh666D](https://avatars.discourse-cdn.com/v4/letter/v/b9bd4f/32.png) [@Vignesh666D](https://gromacs.bioexcel.eu/u/Vignesh666D)\
**Post date:** [June 5, 2024, 9:36am UTC](https://gromacs.bioexcel.eu/t/system-is-not-equillibriating-well/9308/1 "2024-06-05T09:36:45Z")

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GROMACS version:  
GROMACS modification: Yes/No  
Here post your question  
I am trying to equilibrate my system consisting of a monolayer membrane temperature coupling I used v-rescale and pressure coupling I used Berendsen isotropic I ran for 1ns and 10 ns both temperature averages I got good but the pressure average is very low 0.38 sometimes membrane gets cleaved. parameters used for pressure coupling are,  
tau\_p 5.0 compressibility 4.5e-5 and ref\_p 1.0 kindly help me with these

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**Author:** ![Karis](https://avatars.discourse-cdn.com/v4/letter/k/ed8c4c/32.png) [@Karis](https://gromacs.bioexcel.eu/u/Karis)\
**Post date:** [June 6, 2024, 9:16am UTC](https://gromacs.bioexcel.eu/t/system-is-not-equillibriating-well/9308/2 "2024-06-06T09:16:54Z")

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Could you share a visualization of the structure, the commands you used to set it up and copy-paste the output from the commands (notes, warnings, errors, etc)? Essentially, the more info the better