# Usage of different versions of GROMACS

**URL:** <https://gromacs.bioexcel.eu/t/usage-of-different-versions-of-gromacs/5400>\
**Category:** User discussions\
**Created:** [December 9, 2022, 2:45pm UTC](https://gromacs.bioexcel.eu/t/usage-of-different-versions-of-gromacs/5400 "2022-12-09T14:45:36Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![ARC](https://avatars.discourse-cdn.com/v4/letter/a/67e7ee/32.png) [@ARC](https://gromacs.bioexcel.eu/u/ARC)\
**Post date:** [December 9, 2022, 2:45pm UTC](https://gromacs.bioexcel.eu/t/usage-of-different-versions-of-gromacs/5400/1 "2022-12-09T14:45:36Z")

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I have simulated a protein-ligand system using GROMACS 2020.6. Later, I extended the simulation and subjected it to production using GROMACS 2020.3. I didn’t encounter any error while executing the above steps. Will usage of different versions affect the accuracy of the trajectory?

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**Author:** ![hess](https://dub1.discourse-cdn.com/flex017/user_avatar/gromacs.bioexcel.eu/hess/32/416_2.png) [@hess](https://gromacs.bioexcel.eu/u/hess)\
**Post date:** [December 9, 2022, 2:57pm UTC](https://gromacs.bioexcel.eu/t/usage-of-different-versions-of-gromacs/5400/2 "2022-12-09T14:57:00Z")

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If mdrun allows you to the extend the run by reading a checkpoint file, there are never accuracy issues. It might be good to check whether bugs were fixed between the two versions that might affect your results.