# Why is reading charmm36 ff files slow in HPC **URL:** \ **Category:** User discussions\ **Created:** [November 27, 2024, 9:22pm UTC](https://gromacs.bioexcel.eu/t/why-is-reading-charmm36-ff-files-slow-in-hpc/10652 "2024-11-27T21:22:31Z")\ **Posts on this page:** 2\ **Page:** 1
**Author:** ![abdulla](https://avatars.discourse-cdn.com/v4/letter/a/c6cbf5/32.png) [@abdulla](https://gromacs.bioexcel.eu/u/abdulla)\ **Post date:** [November 27, 2024, 9:22pm UTC](https://gromacs.bioexcel.eu/t/why-is-reading-charmm36-ff-files-slow-in-hpc/10652/1 "2024-11-27T21:22:31Z")
GROMACS version: GROMACS modification: Yes/No Here post your question First, i have just installed GROMACS 2024 on a HPC … first time i used miniconda -i got the normal gmx version - and it worked very fine for me till i tried to use CHARMM36 FF, i noticed that the file reading is SLOW … for example while reading lipid files it takes over 30 mins idk why or how … i tried installing it manually using this cmake -DCMAKE\_INSTALL\_PATH=\*\*\*\*/data/installed\_pkgs/gromacs24/ -DGMX\_BUILD\_OWN\_FFTW=ON -DREGRESSIONTEST\_DOWNLOAD=ON -DGMX\_MPI=on -DCMAKE\_CXX\_COMPILER=/eb/software/GCCcore/12.3.0/bin/g++ -DCMAKE\_C\_COMPILER=/eb/software/GCCcore/12.3.0/bin/gcc i used OpenMPI 4.1.5 too first i want to be able to use the power of the HPC if u have a better cmake pls tell me second … i tried installing GROMACS in my linux -debian 12- and it worked fine … no slowness or anything … is that normal ?! Thanks for your time ---
**Author:** ![abdulla](https://avatars.discourse-cdn.com/v4/letter/a/c6cbf5/32.png) [@abdulla](https://gromacs.bioexcel.eu/u/abdulla)\ **Post date:** [November 27, 2024, 9:25pm UTC](https://gromacs.bioexcel.eu/t/why-is-reading-charmm36-ff-files-slow-in-hpc/10652/2 "2024-11-27T21:25:23Z")
GPU and CPU models are → CPU : 2x Intel Xeon E5-2680 v3 GPU : NVIDIA Tesla K80