# \#hardware

**URL:** https://gromacs.bioexcel.eu/tag/hardware/21.md

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## [Hardware advice: RTX 5080 vs 5090 for 50k-100k atom protein systems](https://gromacs.bioexcel.eu/t/hardware-advice-rtx-5080-vs-5090-for-50k-100k-atom-protein-systems/13738)

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**Author:** [@isjeong929](https://gromacs.bioexcel.eu/u/isjeong929)\
**Replies:** 1\
**Last updated:** [October 2, 2026, 12:47pm UTC](https://gromacs.bioexcel.eu/t/hardware-advice-rtx-5080-vs-5090-for-50k-100k-atom-protein-systems/13738 "2026-10-02T12:47:22Z")

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GROMACS version: 2026.3 (planned — conda-forge CUDA build) GROMACS modification: No Building two workstations for protein MD at a small research group (two users, one machine each). Would appreciate input from people…

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## [Low GROMACS performance on RTX 4090](https://gromacs.bioexcel.eu/t/low-gromacs-performance-on-rtx-4090/6083)

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**Author:** [@EgorBulavko](https://gromacs.bioexcel.eu/u/EgorBulavko)\
**Replies:** 3\
**Last updated:** [April 6, 2023, 3:51pm UTC](https://gromacs.bioexcel.eu/t/low-gromacs-performance-on-rtx-4090/6083 "2023-04-06T15:51:17Z")

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GROMACS version: 2023 GROMACS modification: No Dear community! I have two slightly different PC assemblies both based on RTX 4090 GPU, which differ in GROMACS performance more than twice. I have no idea about the reas…

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## [Regarding Editing the RAM and Compiling from GROMACS Source to improve performance](https://gromacs.bioexcel.eu/t/regarding-editing-the-ram-and-compiling-from-gromacs-source-to-improve-performance/4079)

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**Author:** [@pssahoo](https://gromacs.bioexcel.eu/u/pssahoo)\
**Replies:** 0\
**Last updated:** [April 27, 2022, 5:01am UTC](https://gromacs.bioexcel.eu/t/regarding-editing-the-ram-and-compiling-from-gromacs-source-to-improve-performance/4079 "2022-04-27T05:01:40Z")

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GROMACS version: 2021.3 GROMACS modification: Yes Here post your question Hi Where do I find the details of the CPU RAM which can be edited from current default limit of 16GB RAM to 32 GB RAM and then compile GROMACS a…