A problem about simulating the evaporation of solution

GROMACS version: 2019.4-plumed
GROMACS modification: Yes

A problem about simulating the evaporation of solution

I simultated the evaporation of solution affect the structure of protein, but when I run the nvt.mdp the gromacs warning us the imformation as following picture. If the protein structure has problem? How should I do to solve this phenomenon? To correct the itp or gro of protein?