Hamiltonian replica exchange error

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1

GROMACS version: 2025.2
GROMACS modification: Yes

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I am currently using GROMACS 2025.2 with PLUMED 2.10 and trying to run Hamiltonian replica exchange (HREX). However, I get the following error when using the -hrex option:

-hrex parameter does not exist

I observe the same behavior when using GROMACS 2025.2 with PLUMED 2.9.2.

Interestingly, HREX works correctly when using GROMACS 2024.4 with PLUMED 2.9.4.

I would therefore like to know whether HREX support has been removed or changed in GROMACS 2025 and later versions, or whether this is related specifically to the PLUMED interface with GROMACS 2025.

Is there currently a supported way to run Hamiltonian replica exchange with GROMACS 2025.x and PLUMED?

Thanks in advance.

2

This is a question for PLUMED, not GROMACS.