Is there an especial force field for md simulation of biological systems without water molecules

[shanza]

Hello Sir, can you please help me regarding this issue.

Urgent help: System has non-zero total charge

How i can solve this issue? I read in one discussion that we can use -maxwarn option for this issue. but when i used this, it says the command line is not correct. it is showing the following warning: WARNING 1 [file topol.top, line 51]: You are using Ewald electrostatics in a system with net charge. This can lead to severe artifacts, such as ions moving into regions with low dielectric, due to the uniform background charge. We suggest to neutralize your system with counter ions, possibly…