Simulation box size

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GROMACS modification: Yes/No
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Hi to all!
I would like to know if there is no problem in changing the z dimension of the pbc box in a protein structure which has been processed through all the MD protocol (minimization, equilibration in NVT, production) in any of the output files as to use it as an initial configuration for another simulation to be enssambled with another system with equal pbc box dimensions.