When I fill the ions, I get an error and the solvent cannot be found in the topology file。

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GROMACS version:2022.2
GROMACS modification: Yes/No
Here post your question ：The specific error is as follows：ERROR 1[file 112.top, line 14]: No suh moleculetype SOL

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Would you be able to post what commands you were using up to this point? It seems like something went wrong with one of your earlier steps

Also, this might be a potential solution if the problem is just that the solvent topology wasn’t specified in the topology file: chemistry - How to fix GROMACS error 'No such moleculetype SOL'? - Stack Overflow