Restraining a protein with respect to a transformed structure

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1

GROMACS version: 2019.6
GROMACS modification: No

Dear all,

I have a protein-water system with four chains lying at a specific distance from each other. I would like to restrain the equilibrated protein structure with respect to a transformed structure in which the four chains are farther apart from each other and continue the simulation. However, I cannot use the pull option. Is there any tool or any approach that I can use to gradually restrain the protein to this specific structure. Of course if I directly restrain the protein to this structure, the simulation crashes.

I would appreciate your help.

Best regards,
Azadeh