Error in (gmx grompp -f ions.mdp -c solv.gro -p topol.top -o ions.tpr)

GROMACS version:
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This is the error I keep getting:

Here is everything about the error from the terminal:

Executable: /opt/homebrew/bin/…/Cellar/gromacs/2024.3/bin/gmx

Data prefix: /opt/homebrew/bin/…/Cellar/gromacs/2024.3

Working dir: /Users/arneshbanerjee/Downloads

Command line:

gmx grompp -f ions.mdp -c solv.gro -p topol.top -o ions.tpr

Ignoring obsolete mdp entry ‘title’

Ignoring obsolete mdp entry ‘ns_type’

Setting the LD random seed to 2046558205

Generated 330891 of the 330891 non-bonded parameter combinations

Generating 1-4 interactions: fudge = 0.5

Generated 330891 of the 330891 1-4 parameter combinations

Excluding 3 bonded neighbours molecule type ‘Protein_chain_A’

Excluding 3 bonded neighbours molecule type ‘Protein_chain_B’

Excluding 2 bonded neighbours molecule type ‘SOL’

NOTE 1 [file topol.top, line 50]:

System has non-zero total charge: -33.000000

Total charge should normally be an integer. See

Floating point arithmetic - GROMACS 2025.1 documentation

for discussion on how close it should be to an integer.

atom name 27 in topol.top and solv.gro does not match (OG - CG)

atom name 27 in topol.top and solv.gro does not match (OG - CG)

atom name 28 in topol.top and solv.gro does not match (HG - HG1)

atom name 28 in topol.top and solv.gro does not match (HG - HG1)

atom name 29 in topol.top and solv.gro does not match (C - HG2)

atom name 29 in topol.top and solv.gro does not match (C - HG2)

atom name 30 in topol.top and solv.gro does not match (O - SD)

atom name 30 in topol.top and solv.gro does not match (O - SD)

atom name 31 in topol.top and solv.gro does not match (N - CE)

atom name 31 in topol.top and solv.gro does not match (N - CE)

atom name 32 in topol.top and solv.gro does not match (H - HE1)

atom name 32 in topol.top and solv.gro does not match (H - HE1)

atom name 33 in topol.top and solv.gro does not match (CA - HE2)

atom name 33 in topol.top and solv.gro does not match (CA - HE2)

atom name 34 in topol.top and solv.gro does not match (HA - HE3)

atom name 34 in topol.top and solv.gro does not match (HA - HE3)

atom name 35 in topol.top and solv.gro does not match (CB - C)

atom name 35 in topol.top and solv.gro does not match (CB - C)

atom name 36 in topol.top and solv.gro does not match (HB1 - O)

atom name 36 in topol.top and solv.gro does not match (HB1 - O)

atom name 37 in topol.top and solv.gro does not match (HB2 - N)

atom name 37 in topol.top and solv.gro does not match (HB2 - N)

atom name 38 in topol.top and solv.gro does not match (CG - H)

atom name 38 in topol.top and solv.gro does not match (CG - H)

atom name 39 in topol.top and solv.gro does not match (HG1 - CA)

atom name 39 in topol.top and solv.gro does not match (HG1 - CA)

atom name 40 in topol.top and solv.gro does not match (HG2 - HA)

atom name 40 in topol.top and solv.gro does not match (HG2 - HA)

atom name 41 in topol.top and solv.gro does not match (CD - CB)

atom name 41 in topol.top and solv.gro does not match (CD - CB)

atom name 42 in topol.top and solv.gro does not match (HD1 - HB1)

atom name 42 in topol.top and solv.gro does not match (HD1 - HB1)

atom name 43 in topol.top and solv.gro does not match (HD2 - HB2)

atom name 43 in topol.top and solv.gro does not match (HD2 - HB2)

atom name 44 in topol.top and solv.gro does not match (CE - CG)

atom name 44 in topol.top and solv.gro does not match (CE - CG)

atom name 45 in topol.top and solv.gro does not match (HE1 - HG1)

atom name 45 in topol.top and solv.gro does not match (HE1 - HG1)

atom name 46 in topol.top and solv.gro does not match (HE2 - HG2)

atom name 46 in topol.top and solv.gro does not match (HE2 - HG2)

(more than 20 non-matching atom names)

(more than 20 non-matching atom names)

WARNING 1 [file topol.top, line 50]:

12086 non-matching atom names

atom names from topol.top will be used

atom names from solv.gro will be ignored

Analysing residue names:

There are: 796 Protein residues

There are: 362779 Water residues

Analysing Protein…

Number of degrees of freedom in T-Coupling group rest is 2214396.00

The integrator does not provide a ensemble temperature, there is no
system ensemble temperature

NOTE 2 [file ions.mdp]:

You are using a plain Coulomb cut-off, which might produce artifacts.

You might want to consider using PME electrostatics.

This run will generate roughly 84 Mb of data

There were 2 NOTEs

There was 1 WARNING


Program: gmx grompp, version 2024.3-Homebrew

Source file: src/gromacs/gmxpreprocess/grompp.cpp (line 2751)

Fatal error:

Too many warnings (1).

If you are sure all warnings are harmless, use the -maxwarn option.

Try running with -maxwarn option and you would get all the warnings while your ion addition would go good.

gmx grompp -f ions.tpr -c solv.gro -p topol.top -o ions.tpr -maxwarn 3

Typically, this results from net charge of the system. It also looks like you have some atom name mis-match.