Forcefield recommendations for protein-ligand system

GROMACS version:2023.2-Homebrew
GROMACS modification: Yes/No
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I am studying a small protein and a small molecule . I have found that there are many forcefields that can be used for protein-ligand studies, but I am not sure which one is the best fit for my research.
Therefore, I would like to ask for your advice on the forcefield that is most suitable for my study, considering the following factors:

  • Accuracy of the forcefield
  • Speed of the simulation

I would be grateful for any advice you can provide.

Thank you for your time and consideration.

Sincerely,
Panuwid