Is the frame interval important for studying the membrane properties?

can anybody please help!!!
I want to study the properties of the membrane by comparing 6 systems of different lipid acyl chains and phospholipids which I have built using charmm-gui, and for which I have setup my atomistic simulation for 500ns and the frame interval is 100ps. the frame interval which I have setup will it be sufficient for studying the membrane properties or 10ps frame interval will make in detail differentiation for different membranes? either 100ps or 10ps in both the cases I would be able to see the differences, right??

What phenomena are you interested in? Lipids tend to be slow. If you are interested into equilibrium properties such as average area per lipid, order parameters of the tails, average thickness etc I would say that 100ps is okay, I’d rather collect more statistics in terms of having long production runs.