'topol' does not exist or is not accessible

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1

GROMACS version:
GROMACS modification: Yes/No
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Hi guys,
During the simulation of a peptide, I am facing the following error: How can i solve it ?

GROMACS: gmx mdrun, VERSION 5.1.2
Executable: /opt/gromacs/bin/gmx
Data prefix: /opt/gromacs
Command line:
gmx mdrun -deffnm nvt-pr

Program: gmx mdrun, VERSION 5.1.2
Source file: src/gromacs/options/options.cpp (line 248)
Function: void gmx::Options::finish()

Error in user input:
Invalid input values
In option s
Required option was not provided, and the default file ‘topol’ does not
exist or is not accessible.
The following extensions were tried to complete the file name:
.tpr

2

There is no such file called “nvt-pr.tpr” in the working directory, and mdrun also cannot find the default file name “topol.tpr” so it is bailing out.

Also, it is wise to use a newer version of GROMACS. Version 5.1.2 is absolutely ancient and no longer supported.

3

Hi, this error will appear if the name of the .tpr file is not the same as the output file of the mdrun command.