GROMACS modification: No
Here post your question
Basically, my system was blowing up whenever I ran the production run. I tried almost everything for a month or so by reading the forums and questions related to the same.
After numerous attempts turning couple-intramol value to yes my production run ran fine .
I just want to know that turning this on is useful or not and why its default value is no .
I have a multi protein system on lipid membrane and has used parameterized CHARMM force field on GROMACS 2020.6.
I am new to the field and would be highly thankful if someone could spare there time to help me out here.
Thanks in advance.