Ligand addition to a membrane protein - lipid bilayer system and Gromacs Simulation?

GROMACS version:2018

I used CHARMM GUI to incorporate the protein into the membrane lipid bilayer after sugar addition, now I want to add a ligand to the system using GROMACS, is there any step-by-step procedure for the ligand addition followed by GROMACS Simulation.

Thank you very much in advance.